NSAIDS RELIEVE THE INFLAMMATION AND PAIN ASSOCIATED WITH OA
- NSAIDs inhibit the cyclooxygenase (COX-1 and COX-2) enzymes from producing prostaglandins which are mediators of inflammation and pain6-8
- NSAIDs are also known to have an analgesic effect6
SIGNS OF OA
Treatment should aim to relieve both the inflammation and pain associated with OA.
EXPERT RECOMMENDATIONS
Oral NSAIDs are the oral medications of choice for the treatment of OA and are strongly recommended in knee, hip, and/or hand OA. Topical NSAIDs are strongly recommended in knee OA4
Recommends oral and topical NSAIDs as first-line pharmacologic treatment options for OA5
HOW NSAIDS WORK